News

April 24, 2015April 24, 2015

Researchers Reduce Mutated Mitochondrial Genomes Implicated in Mitochondrial Diseases

News

Results from a recent study published in the journal Cell provide a new potential therapeutic avenue for preventing the transgenerational transmission of human mitochondrial diseases caused by mutations in mtDNA, ... Read more

April 23, 2015April 23, 2015

CHOP Researchers Restore Cellular Energy Signals, Offering Possibility of Treating Mitochondrial Diseases

News

Mitochondrial disorders are complex conditions for which few treatments are available. Now, using microscopic worms, researchers at The Children’s Hospital of Philadelphia (CHOP), are researching if existing human drugs aimed at improving metabolism ... Read more

April 21, 2015April 21, 2015

Researchers Discover Mitochondrial Mutation That Leads to Fatty Liver Disease

News

In a new study entitled “Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction,” researchers discovered a mutation in a mitochondrial ribosome that induces mitochondria dysfunction leading to heart ... Read more

April 20, 2015April 20, 2015

Two New Mutations in Mitochondria DNA Associated with Isolated Myopathy

News

In a new study entitled “Pathogenic mitochondrial mt-tRNAAla variants are uniquely associated with isolated myopathy,” authors report to have identified in two patients with isolated myopathy (a muscular disease characterized ... Read more

April 17, 2015April 26, 2015

Researchers Discover That For Mitochondrial Diseases, The Problem Lies Within

News

Researchers at The Children’s Hospital of Philadelphia (CHOP) headed by Marni J. Falk, M.D., director and attending physician in the Mitochondrial-Genetic Disease Clinic, focused on a group of respiratory enzymes ... Read more

March 31, 2015March 31, 2015

Study Identifies New Mutations of Mitochondrial Disorders Associated with CoQ10 Deficiency

News

A collaborative team of German and Italian researchers from the Institute of Human Genetics (Neuherberg) and the Istituto di Ricovero e Cura a Carettere Scientifico (Milan) identified mutations in the ... Read more

March 18, 2015March 20, 2015

Cutting-edge Imaging Techniques Reveal New mtDNA Control Processes That May Be Involved In Mitochondrial Diseases

Mitochondrial Myopathy News, News

Mitochondria consist of small structures having evolved from bacteria engulfed by cells. This bacterial origin explains why mitochondria has its own genetic material (mitochondrial DNA, mtDNA) distinct from the nuclear ... Read more

March 17, 2015March 17, 2015

Vitamin B3 Found to Rescue Mitochondria Defects in Adults with Mitochondrial Myopathy

Mitochondrial Myopathy News, News

In a new study entitled “Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3,” an international team of researchers show that a vitamin B3 form, nicotinamide riboside, is ... Read more

March 12, 2015March 16, 2015

Case Report Explores Mitochondrial Myopathy with Rapidly Progressive Adult-onset Scoliosis

Mitochondrial Myopathy News, News

In a recent article published in Acta Neuropathologica Communications, a team of researchers from the University of California San Francisco reported a case of a patient with a rapid progressive ... Read more

March 10, 2015March 10, 2015

Prenatal Diagnostic Testing for Mitochondrial Diseases May Help Future Parents, UK Study Shows

Mitochondrial Myopathy News, News

Researchers studied the prenatal diagnostic services provided in the UK for mitochondrial diseases since 2007. The study entitled “A national perspective on prenatal testing for mitochondrial disease” was published on ... Read more

March 9, 2015March 9, 2015

Reata Announces Enrollment of First Patient in Phase 2 Study of RTA 408 for the Treatment of Friedreich’s Ataxia

Friedreich's Ataxia, News

Irving, Texas based Reata Pharmaceuticals, whose mission is to translate innovative research into breakthrough medicines for difficult-to-treat diseases that have significant unmet needs, recently announced the enrollment of their first patient ... Read more

March 4, 2015March 20, 2015

Brain and Muscle Disorders may be Caused by a Dysfunctional Mitochondrial Calcium Channel

News

A collaboration between researchers from Leeds’ St. James’s University Hospital, University College London (UCL) and the Institute of Child Health (UCL) identified a gene mutation affecting mitochondrial calcium (Ca2+) levels ... Read more

February 27, 2015February 27, 2015

University of Helsinki Researchers Discover Vitamin B3 Form that is Effective in Attenuating Mitochondrial Myopathy Progression

Mitochondrial Myopathy News, News

Researchers from the University of Helsinki recently found that a vitamin B3 form might be effective in attenuating the progression of mitochondrial myopathy. The study is published in the journal ... Read more

February 25, 2015February 26, 2015

University of Geneva Researchers Discover New Mitochondrial Activity Component Previously Undetected In Mammals

News

Mitochondria, the true energy power plants of cellular activity, play a vital role in energy production and in several other essential cellular processes, including lipid and amino acid metabolism, the ... Read more

February 23, 2015February 23, 2015

Individual Case Report Highlights Rare Acute Kidney Injury Leading To Mitochondrial Myopathy

Mitochondrial Myopathy News, News

A recent case report of a patient with acute kidney injury who was later diagnosed with mitochondrial myopathy, titled “Recurrent episodic acute kidney injury as presenting manifestation of mitochondrial myopathy,” ... Read more

February 20, 2015February 23, 2015

Toxins Crossing the Placental Barrier Can Lead To Mitochondrial Toxcicity, Diseases

Mitochondrial Myopathy News, News

A recent controversial decision to legalize “three parent babies” in the United Kingdom has led researchers to believe that they may have found a solution for heading off genetically transferred Mitochondrial Diseases ... Read more

February 19, 2015

Stealth BioTherapeutics Initiates Clinical Study of Bendavia for the Treatment of Mitochondrial Myopathy

Mitochondrial Myopathy News, News

Stealth BioTherapeutics, a biopharmaceutical company developing treatments for rare, mitochondria-related diseases, recently announced the initiation of a new clinical study of Bendavia for the treatment of Mitochondrial Myopathy (MM). Mitochondrial Myopathy (MM) ... Read more

February 16, 2015February 17, 2015

MitoAction hosts 4th Mitochondrial Disease Clinical Conference

News

As part of its ongoing effort to improve mitochondrial disease patient care, MitoAction — a nonprofit organization dedicated to improving the quality of life for children, adults, and families living with mitochondrial ... Read more

February 12, 2015February 12, 2015

Coenzyme Q10 Deficiency Linked To Rare Mitochondrial Disease Found Mainly In Children

News

A new international study by scientists at the University of Granada (UGR) in Spain, the University of Wisconsin-Madison, Columbia University in New York, and Rutgers, The State University of New ... Read more