News

February 24, 2017

Phase 2/3 Trial Will Evaluate Bardoxolone Methyl as Treatment for Alport-related CKD

News

Reata Pharmaceuticals has begun screening patients for the new Phase 2/3 trial evaluating bardoxolone methyl as a treatment for patients of Alport syndrome-associated chronic kidney disease (CKD). The aim of ... Read more

February 22, 2017

Study Identifies CKD Patient Risk Groups for Adverse Drug Interactions

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Patients diagnosed with chronic kidney disease (CKD) who take a lot of prescription medications, have long hospital admissions, have hypertension or who are mature adults (but younger than 60) are ... Read more

February 20, 2017

Limiting Salt Intake Lowers Blood Pressure in CKD Patients, Study Shows

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Limiting the consumption of salt lead to reduced blood pressure in patients with chronic kidney disease (CKD), new research suggests. The findings will be published in an upcoming issue of ... Read more

February 17, 2017

End-Stage Renal Disease Therapeutic Tenapanor Does Well in Phase 3 Clinical Trial

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Tenapanor, a therapeutic for end-stage renal disease patients who are on dialysis and have too much phosphate in their blood, was well-tolerated and met the goals of a Phase 3 ... Read more

February 15, 2017

Armetheon, FDA Reach Agreement Prior to New Drug Filing for Tecarfarin

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Armetheon and the U.S. Food and Drug Administration (FDA) have reached an agreement for a Phase 3 trial of drug candidate Tecarfarin, prior to a new drug application (NDA) filing projected ... Read more

February 13, 2017

Nephrology Society and VA Join Forces on Best Approaches to Kidney Disease

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The American Society of Nephrology (ASN) partnered with the U.S. Department of Veterans Affairs (VA) to host the Kidney Innovation Summit, aimed at advancing best practices and sharing insights in chronic ... Read more

February 10, 2017

FDA Approves Amgen’s Parsabiv for Secondary Hyperparathyroidism in Adults on Dialysis

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The U.S. Food and Drug Administration (FDA) has approved Amgen’s Parsabiv (etelcalcetide) to treat adult patients with chronic kidney disease (CKD) who are on dialysis and experience secondary hyperparathyroidism (sHPT). “We are ... Read more

February 8, 2017

Higher Serum Levels of Klotho Protein May Protect Kidney Function, Study Finds

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Higher levels of the klotho protein may protect the kidney from declining function, a new study reports. These findings suggest that klotho may serve as a potential therapeutic target for the ... Read more

February 6, 2017

Skin’s Sodium Content Linked to Heart Problems in Kidney Disease Patients, Study Shows

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Sodium intake may be linked with the changes that occur in the heart’s left ventricle of patients with chronic kidney disease (CKD). Interventions that reduce sodium intake, such as reducing ... Read more

February 3, 2017February 3, 2017

Itching Caused by CKD, Often Overlooked, May Have Treatments on the Way

News

An article reviewing potential new treatments for the management of itching related to chronic kidney disease (CKD) has been published in the International Journal of Nephrology and Renovascular Disease.

February 1, 2017February 1, 2017

Depression Often Undertreated in Kidney Disease Patients on Chronic Dialysis

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Patients on chronic hemodialysis due to kidney failure often suffer from depression but they frequently show no interest in modifying or starting anti-depressant therapy, and specialists are often unwilling to ... Read more

January 30, 2017

EMA Starts Accelerated Review of G/P Regimen, Possible Treatment Option for Severe CKD

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The European Medicines Agency (EMA) has begun an accelerated review of AbbVie’s marketing authorization application for a glecaprevir/pibrentasvir (G/P) regimen to treat major Hepatitis C virus (HCV) genotypes, and as a potential alternative ... Read more

January 27, 2017

Oral Iron Therapy Seen to Be Effective in Small Clinical Trial for Anemic CKD Patients

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An oral iron formulation composed of ferric citrate shows potential as a treatment for anemia in patients with iron deficiency associated with chronic kidney disease (CKD). The study, “Effects of ... Read more

January 25, 2017

Harvard Study Reviews Impact of Affordable Care Act in Chronically Ill Patients

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The Affordable Care Act (ACA), commonly known as ObamaCare, has been evaluated in a new research study regarding its impact in Americans living with chronic diseases, like chronic kidney disease ... Read more

January 23, 2017January 23, 2017

Espero Donates GoNitro to ISCHEMIA and ISCHEMIA-CKD Clinical Trials

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Espero Pharmaceuticals will donate its GoNitro (nitroglycerin) sublingual powder to be used in two clinical trials in patients with stable ischemic heart disease, and in a subgroup of patients who also ... Read more

January 20, 2017January 20, 2017

NAACP Leads Effort to Raise Awareness of Kidney Disease, Care Among African-Americans

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African-Americans are nearly four times more likely than white Americans to develop kidney failure, according to the National Institute of Diabetes and Digestive and Kidney Diseases, and a reason for an ... Read more

January 18, 2017

Leading Physician Organizations Issue New Guideline for Treating Hypertension in Older Adults

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There is a new clinical practice guideline for the treatment of hypertension, often associated with chronic kidney disease (CKD), thanks to the joint work of two leading physician organizations, namely the American College ... Read more

January 16, 2017January 16, 2017

Tricida’s Therapy Candidate Shows Promise in Restoring Acid-base Balance in Kidney Disease Patients

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Tricida‘s lead investigational drug TRC101 increased serum bicarbonate levels essential to restoring the acid-base balance in patients with chronic kidney disease (CKD) and metabolic acidosis, according to the results of a study. ... Read more

January 13, 2017

2 Clinical Trials Begin to Evaluate Potential Hyperkalemia Treatment

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Two trials have been initiated to assess Ardelyx‘s RDX227675 as a treatment for patients with hyperkalemia, a serious condition in people with chronic kidney disease (CKD) and heart failure (HF). ... Read more

January 11, 2017

Early Consultation May Not Improve Short-term Survival in Kidney Patients

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Early consultation with specialists failed to help elderly patients with acute kidney damage survive longer, according to a study. One reason is that many of those who see a nephrologist ... Read more